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Systematic Reviews

This guide explains systematic reviews and provides tools, strategies, and library resources to help you plan and carry out your research.

Guidelines

Refer to the following guidelines and standards:

Note. PRISMA 2020 is the internationally recognized standard for reporting systematic reviews and meta-analyses; use the PRISMA 2020 Checklist and the PRISMA 2020 Flow Diagram alongside any journal-specific guidelines.


Below are the main sections and recommended items according to the PRISMA 2020 Checklist:

Title

Abstract

Introduction

  • Rationale for the review
  • Objectives

Methods

  • Eligibility criteria
  • Information sources
  • Search strategy
  • Selection process
  • Data collection process
  • Data items
  • Study risk of bias assessment
  • Effect measures
  • Synthesis methods
  • Reporting bias assessment
  • Certainty assessment

Results

  • Study selection
  • Study characteristics
  • Risk of bias in studies
  • Results of individual studies
  • Results of syntheses

Discussion

Other Information

  • Registration and protocol
  • Support
  • Competing interests
  • Availability of data, code, and other materials

Items Related to the Search Strategy

Keep in mind when writing the “Search Methods” section:

Objectives of the methods section:

  • Transparency
    • Describe the measures taken to minimize bias
    • Explain the steps used to ensure comprehensive coverage of the evidence
  • Reproducibility
    • Provide sufficient detail to allow others to reproduce the search strategy

Writing tips:

Consider your audience: Who is likely to read the methods section? You may need to explain elements that seem obvious. Write a detailed account of what was done.


Key points from the PRISMA 2020 Checklist regarding the search strategy

Information sources

  • Date of last search: Report the date when the search was last run.
  • Databases and websites consulted: List the full name of each database, website (with links), and registry searched.
  • Platforms and coverage periods: Specify the platforms used to access the databases and the time spans covered.
  • Handsearching: Describe the journals or conferences manually screened.
  • Citation searching: Indicate whether citation searching was conducted.
  • Reference list checking: Explain how reference lists were selected and analyzed.
  • Author contact strategy: Describe the method used to contact authors, if applicable.

Search strategy

  • Search approaches: Line-by-line strategies for complex searches, or sequence of terms for simpler searches.
  • Filters and limits applied: Describe any limits, filters, or search hedges used, with a clear justification (and cite sources if applicable).
  • Tools used: Mention tools employed to automate parts of the process.
  • Validation of the search strategy: Indicate the steps taken to validate the strategy used.
  • Peer review process: Describe any methods used to submit the strategy for peer review.
  • Conceptual framework: Explain the framework used to structure the search (e.g., PICO or another model).

Discussion

  • Limitations of available data:
    • Some relevant studies may be missing (due to strict criteria, languages, or timeframes).
    • The quality and completeness of data in included studies may vary.
    • Access to unpublished studies or grey literature may be limited.
  • Limitations of the review process:
    • Search strategies may be too restrictive or poorly adapted.
    • Potential biases in study selection or data extraction.
    • Time, resource, or tool constraints that may reduce the depth of analysis.
    • Variability among reviewers that could introduce subjectivity.

In the context of a systematic review, it is often recommended to include a detailed appendix documenting the search strategy to ensure transparency and reproducibility. Elements to include:

  • Search summary:
    • Use a summary table or list.
    • Provide the name of each database, the platform used, coverage period, search date, and number of results retrieved.
  • Search updates:
    • Report any information about updated or repeated searches during the project.
  • Exact search details:
    • Include the exact search strings as executed, including any limits applied.
  • Attribution and methodology:
    • Acknowledge any search filters, strategies, or methodological frameworks used to guide or refine the search.
  • Grey literature:
    • Document details of searches conducted in non-traditional sources (grey literature), including methods and tools used.

Suggested Readings

Introduction to PRISMA 2020 and implications for research synthesis methodologists

  • Page, Matthew J., David Moher et Joanne E. McKenzie (2022). Introduction to PRISMA 2020 and implications for research synthesis methodologists, Research Synthesis Methods, vol. 13, no 2, p. 156‑163. https://doi.org/10.1002/jrsm.1535

 

PRISMA-S : An extension to the PRISMA Statement for Reporting Literature Searches in Systematic Reviews

  • Rethlefsen, Melissa L., Shona Kirtley, Siw Waffenschmidt, Ana Patricia Ayala, David Moher,  Matthew J. Page et al. (2021). PRISMA-S : An extension to the PRISMA Statement for Reporting Literature Searches in Systematic Reviews, Systematic Reviews, vol. 10, no 39. https://doi.org/10.1186/s13643-020-01542-z

 

How to properly use the PRISMA Statement

  • Sarkis-Onofre, Rafael, Ferrán Catalá-López, Edoardo Aromataris et Craig Lockwood (2021). How to properly use the PRISMA Statement. Systematic Reviews, vol. 10, no 117. https://doi.org/10.1186/s13643-021-01671-z

Roles

Expert:

  • Write the majority of the sections of the article

Librarian:

  • Assist in drafting the section on literature search methods
  • Prepare the search strategies for inclusion in an appendix
  • Recommend and advise on reporting standards and expectations